Synthesis and Single Crystal Structures of Substituted-1,3-Selenazol-2-amines "2279

نویسندگان

  • Guoxiong Hua
  • Junyi Du
  • Alexandra M. Z. Slawin
  • Derek Woollins
  • Luana Bagnoli
چکیده

The synthesis and X-ray single crystal structures of a series of new 4-substituted-1,3selenazol-2-amines is reported. The efficient preparation of these compounds was carried out by two-component cyclization of the selenoureas with equimolar amounts of α-haloketones. The selenoureas were obtained from the reaction of Woollins’ reagent with cyanamides, followed by hydrolysis with water. All new compounds have been characterized by IR spectroscopy, multi-NMR (1H, 13C, 77Se) spectroscopy, accurate mass measurement and single crystal X-ray structure analysis.

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Synthesis and Single Crystal Structures of Substituted-1,3-Selenazol-2-amines.

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تاریخ انتشار 2016